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Peter G. Stock, M.D., Ph.D.

Professor of Surgery
Surgical Director, Kidney and Pancreas Transplant Program
Surgical Director, Pediatric Renal Transplant Program
Co-Director, Pancreatic Islet Cell Transplant Program
Program, Director, T32 Training Program in Transplant Surgery

Contact Information

Academic Office
(415) 353-8617
peter.stock@ucsf.edu
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  • University of Illinois, Urbana, IL, B.S., Biology, 1974-78
  • University of Illinois, Chicago, IL, M.D., Medicine, 1978-82
  • University of Minnesota, Minneapolis, MN, Ph.D., Surgery, 1985-92
  • University of Minnesota, Intern, General Surgery, 1982-83
  • University of Minnesota, Resident, General Surgery, 1983-90
  • University of California, San Francisco, Fellow, Transplant Surgery, 1990-92
  • American Board of Surgery, 1991
  • Bile Duct Injuries
  • Bile Duct Strictures
  • Cholangiocarcinoma (Bile Duct Cancer)
  • Choledochal Cyst Disease
  • Dialysis Access
  • End-Stage Kidney Disease
  • Fulminant Hepatic Failure
  • Hepatitis B
  • Hepatitis C
  • Hepatocellular Carcinoma (Liver Cancer)
  • Kidney and LIver Transplantation in HIV Patients
  • Kidney Transplantation
  • Liver Transplantation
  • Living Donor Kidney Transplantation
  • Living Donor Liver Transplantation
  • Pancreas Transplantation
  • Pancreatic Islet Cell Transplantation
  • Pediatric Kidney Transplantation
  • Pediatric Liver Transplantation
  • Polycystic Kidney Disease
  • Polycystic Liver Disease
  • Portal Hypertension
  • Induction of transplantation tolerance to block alloimmunity and recurrent autoimmunity following pancreatic islet transplantation
  • Safety and efficacy of solid organ transplantation in people with HIV

Peter G. Stock, M.D., Ph.D. is Professor of Surgery at UCSF, Surgical Director of the Pediatric Renal Transplantation Program and Surgical Director of the Pancreas Transplant Program. He was trained at the University of Minnesota, completing a surgical residency before coming to UCSF for a transplant fellowship. He joined the UCSF faculty in 1992. Dr. Stock specializes in liver, kidney and pancreas transplantation.

For many years, Dr. Stock was Chair of the Department of Surgery Research Committee. Under his  outstanding leadership. he has helped to establish UCSF Surgery as one of the top research programs for surgical residents in the U.S.

clincial investigation on which Dr. Stock served as principal investigator led the passage of the Hope Act lifting the ban on research for transplanting organs between HIV-positive donors and recipients.

Dr. Stock is a frequent presenter on issues related to transplantation and immunosuppression, and holds membership in numerous professional and honorary societies.

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  • James IVth Fellowship Award, US Representative, 2000
  • Faculty Fellowship Award, American College of Surgeons, 1993
  • Sandoz Fellowship Award, American Society of Transplant Surgeons, 1991
  • Outstanding Surgical Resident Teaching Award, Department of Surgery, University of Minnesota, Minneapolis, MN, 1989
  • David Gaviser Award, Outstanding Surgical Research, University of Minnesota, Minneapolis, MN, 1989
  • Outstanding Research Award, Senior Medical Student, University of Illinois, Chicago, IL, 1982
  • Alpha Omega Alpha, University of Illinois, Chicago, IL, 1981
  • Magna Cum Laude, Honors in Biology with High Distinction, University of Illinois, Urbana, IL, 1978
  • Phi Beta Kappa, University of Illinois, Urbana, IL, 1978
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Pancreatic Islet Transplantation
The translational research in the field of pancreatic islets revolves around clinical trials of the safety and efficacy of islet transplantation in patients with Type I diabetes. The clinical trials are funded by the National Institutes of Health (NIH) and the Juvenile Diabetes Research Foundation (JDRF). These clinical trials focus on novel immunosuppressive strategies that utilize co-stimulatory blockade to prevent the immune response against pancreatic islets with a regimen that is not toxic to kidneys or beta cells.

Related research involves improving the techniques required for isolating pancreatic islets from the pancreas, which is being conducted in a fully compliant GMP laboratory facility. The study of the alloimmune and autoimmune response following islet transplantation will be conducted to determine the efficacy of the immunosuppressive strategies. Further translational studies will include methods of expanding the source of beta cells, using direct proliferation, as well as manipulation of precursor cells localized in the adult pancreas. We are currently funded (PI) for a translational grant from California Institute of Regenerative Medicine (CIRM) to bring embryonic stem cell-derived beta cells to a clinical trial.

Solid Organ Transplantation in People with HIV
With the advent of highly active anti-retroviral therapy (HAART), HIV has been a chronic disease. People with HIV are no longer dying from progression of HIV to AIDS, but rather as a result of end stage live disease (viral hepatitis co-infection) and kidney disease (HIV nephropathy). Our laboratory heads up the large NIH-sponsored national multicenter trial which is studying the safety and efficacy of solid organ transplantation in people with HIV. Translational research is exploring the impact of HIV on organ function and the impact of immunosuppression on the immune response against HIV and associated copathogens.

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  • Filling a Void of Research (FAVOR) Training for Transplant Surgeons
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    Aug 2016
    -
    Jul 2021
    Principal Investigator
  • Impact of CCR5 Blockade in HIV+ Kidney Transplant Recipients
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    Aug 2015
    -
    Jul 2020
    Principal Investigator
  • Diabetes Research Center
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    Sep 2002
    -
    Mar 2020
    Co-Investigator
  • Sofosbuvir and Ledipasvir in HIV/HCV Coinfected Pre and Post Liver Transplant
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    Jan 2015
    -
    Dec 2017
    Principal Investigator
  • Solid Organ Transplantation in HIV: Multi-Site Study
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    Aug 2003
    -
    Aug 2013
    Principal Investigator
  • General Clinical Research Center
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    Dec 1974
    -
    Mar 2009
    Co-Investigator
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MOST RECENT PUBLICATIONS FROM A TOTAL OF 235
Data provided by UCSF Profiles, powered by CTSI
  1. Durand CM, Zhang W, Brown D, Yu S, Desai N, Redd A, Bagnasco S, Naqvi F, Seaman S, Doby B, Ostrander D, Bowring MG, Eby Y, Fernandez R, Friedman-Moraco R, Turgeon N, Stock P, Chin-Hong P, Mehta S, Stosor V, Small CB, Gupta G, Mehta SA, Wolfe C, Husson J, Gilbert A, Cooper M, Adebiyi O, Agarwal A, Muller E, Quinn TC, Odim J, Huprikar S, Florman S, Massie A, Tobian AAR, Segev DL. A Prospective Multicenter Pilot Study of HIV-Positive Deceased Donor to HIV-Positive Recipient Kidney Transplantation: HOPE in Action. Am J Transplant. 2020 Jul 23. View in PubMed
  2. Markmann JF, Rickels MR, Eggerman TL, Bridges ND, Lafontant DE, Qidwai J, Foster E, Clarke WR, Kamoun M, Alejandro R, Bellin M, Chaloner K, Czarniecki CW, Goldstein JS, Hering BJ, Hunsicker LG, Kaufman DB, Korsgren O, Larsen CP, Luo X, Naji A, Oberholzer J, Posselt AM, Ricordi C, Senior PA, Shapiro A, Stock PG, Turgeon NA. Phase 3 Trial of Human Islet-after-Kidney Transplantation in Type 1 Diabetes. Am J Transplant. 2020 Jul 06. View in PubMed
  3. Stock PG, Wall A, Gardner J, Domínguez-Gil B, Chadban S, Muller E, Dittmer I, Tullius SG. Ethical Issues in the COVID Era: Doing the Right Thing Depends on Location, Resources, and Disease Burden. Transplantation. 2020 Jul; 104(7):1316-1320. View in PubMed
  4. Syed SM, Gardner J, Roll G, Webber A, Mehta N, Shoji J, Adelmann D, Niemann C, Braun HJ, Mello A, Yao F, Posselt A, Kang SM, Hirose R, Roberts J, Feng S, Ascher N, Stock P, Freise C. COVID-19 and Abdominal Transplant: A Stepwise Approach to Practice During Pandemic Conditions. Transplantation. 2020 Jun 29. View in PubMed
  5. Mannon RB, Armstrong B, Stock PG, Mehta AK, Farris AB, Watson N, Morrison Y, Sarwal M, Sigdel T, Bridges N, Robien M, Newell KA, Larsen CP. Avoidance of CNI and Steroids Using Belatacept - Results of the Clinical Trials in Organ Transplantation 16 Trial. Am J Transplant. 2020 Jun 18. View in PubMed
  6. View All Publications

 

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