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Sarwal Lab »  Lab Members »  Alumni »  Dmitry Rychkov, Ph.D.
Dmitry Rychkov, Ph.D.

Dmitry Rychkov, Ph.D.

  • Postdoctoral Scholar

Contact Information

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Education

M.S. in Physics, Lomonosov Moscow State University, Moscow, Russia

Ph.D. in Physics, University of Southern California, CA, USA

Research Interests

  • Bioinformatics
  • Biomarker DIscovery
  • Genomics
  • High Throughput Data
  • Immunology
  • Metabolomics
  • Organ Transplantation
  • Proteomics
  • Transcriptomics

Biography

Dmitry Rychkov is a Postdoctoral Scholar working in Sirota Lab (ICHS) and Sarwal Lab (Department of Surgery) towards leveraging omics data for organ transplants rejection and rheumatoid arthritis. Dmitry obtained his PhD in Theoretical Physics from USC.

Research Overview

Dmitry's current work is focused on leveraging publicly available omics data and developing applying computational approaches for biomarker and therapeutic discovery in the context of the immune system, in particular organ transplants rejection and rheumatoid arthritis. His research interests lie in developing methods to analyze and integrate various types of high-throughput molecular measurements, including genetic, genomic, transcriptomic, proteomic, antibodiomic, miRNA, metabolomic, and clinical data, for disease diagnostics and therapeutics.

Publications

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  1. Rychkov D, Neely J, Oskotsky T, Yu S, Perlmutter N, Nititham J, Carvidi A, Krueger M, Gross A, Criswell LA, Ashouri JF, Sirota M. Cross-Tissue Transcriptomic Analysis Leveraging Machine Learning Approaches Identifies New Biomarkers for Rheumatoid Arthritis. Front Immunol. 2021; 12:638066. View in PubMed
  2. Zarinsefat A, Hartoularos G, Rychkov D, Rashmi P, Chandran S, Vincenti F, Yee CJ, Sarwal MM. Single-Cell RNA Sequencing of Tocilizumab-Treated Peripheral Blood Mononuclear Cells as an in vitro Model of Inflammation. Front Genet. 2020; 11:610682. View in PubMed
  3. Rychkov D, Sur S, Sirota M, Sarwal MM. Molecular Diversity of Clinically Stable Human Kidney Allografts. JAMA Netw Open. 2021 01 04; 4(1):e2035048. View in PubMed
  4. Neely J, Rychkov D, Paranjpe M, Waterfield M, Kim S, Sirota M. Gene Expression Meta-Analysis Reveals Concordance in Gene Activation, Pathway, and Cell-Type Enrichment in Dermatomyositis Target Tissues. ACR Open Rheumatol. 2019 Dec; 1(10):657-666. View in PubMed
  5. Ashouri JF, Hsu LY, Yu S, Rychkov D, Chen Y, Cheng DA, Sirota M, Hansen E, Lattanza L, Zikherman J, Weiss A. Reporters of TCR signaling identify arthritogenic T cells in murine and human autoimmune arthritis. Proc Natl Acad Sci U S A. 2019 09 10; 116(37):18517-18527. View in PubMed

 

 
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