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Minnie M. Sarwal M.D., Ph.D., FRCP, DCH

Minnie M. Sarwal M.D., Ph.D., FRCP, DCH

Professor of Surgery, Medicine, Pediatrics
Professor (Adj), Stanford University, UC Berkeley
Director, Precision Transplant Medicine, UCSF
Co-Director, T32 Training Grant, Transplant Surgery, UCSF

Contact Information

Box 0780
513 Parnassus Ave, Med Sci Room S1268
San Francisco, CA 94143
minnie.sarwal@ucsf.edu
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La Martiniere, Calcutta, India, English Language and Literature, I.S.C.,1981

Calcutta Medical College, Calcutta, India, M.D.,1985

Diploma in Child Health (D.C.H.), London, UK, with distinction 1989

Cambridge University, U.K, Ph.D.,1995

  • Residency (Medicine and Surgery), Calcutta Medical College, India, 06/1986-06/1987
  • Senior House Officer (Pediatrics and Surgery), Calcutta Medical College, India. Advisors: Sir Keith Peters, Sir Cyril Chantler and Sydney Brenner, 06/1987-02/1988
  • Senior House Officer, General Pediatrics & Neonates, Good Hope Hospital, Sutton Coldfield, Birmingham, UK, 02/-07/1989
  • Senior House Officer, General Pediatrics & Neonates, Grantham and Kesteven Hospital, Granthan (GKGH), UK, 03/1988-02/1989
  • Senior House Officer, Neonatology, Leicester Royal Infirmary (LRI), Leicester, UK, 08/-11/1989
  • Senior House Officer, General Pediatrics & Neonates, Leicester General Hosp. (LGH), Leicester, UK, 12/89- 03/90
  • Registrar, Pediatric Cardiology and Cardiothoracic Surgical Unit, Groby Road Hospital, (GRH), Leicester, UK, 04/90-07/90
  • Senior House Officer, Pediatric Nephrology Unit, Guy's Hospital, London, UK, 08/90-10/90
  • Lecturer/Registrar, Pediatric Unit, Guy's Hospital, London, UK, 10/90-09/91
  • Lecturer/Senior Registrar,  Pediatric Nephrology, Dept. of Pediatrics, Guy's Hospital, London, U.K., 10/92-07/95
  • Fellowship in Nephrology, Department of Pediatrics, Addenbrooke's Hospital, Cambridge, 10/91-09/92
  • Ph.D., Molecular Genetics Unit, Christs College, Cambridge University, 10/92-12/95 
  • Acute Kidney Failure
  • Chronic Kidney Disease
  • Cystinosis
  • End-Stage Renal Disease
  • Kidney Transplant Clinical Trials
  • Methylmalonic acidemia
  • Oxalosis
  • Pediatric Bone and Mineral Disorders
  • Pediatric Kidney Transplantation
  • Pediatric Transplant Nephrology
  • Transplant Immunology
  • Genomics
  • Antibiomics
  • GVHD
  • Hepatitis B, C and HIV
  • Metabolomics
  • Organ diseases
  • Proteomics
  • Transplant immunobiology of rejection and tolerance
  • Hindi, Punjab

Minnie M. Sarwal M.D., Ph.D., FRCP, DCH is professor of Surgery, director of the Sarwal Lab, and Precision Transplant Medicine at UCSF. Sarwal is a nationally and internationally recognized leader in the fields of renal and transplant medicine, genomics, proteomics and immunology. She as a deep passion for improving the health of organ transplant recipients by discovering new treatments and investigative approaches for improving outcomes. Prior to joining UCSF, Sarwal was Professor of Surgery, Pediatrics and Immunology at Stanford University, Medical Director of the Pediatric Kidney Transplant Program at Lucille Packard Children's Hospital and Director of the Sarwal Lab.

Sarwal received her M.D. from Calcutta Medical College in India, completed her residency in the UK, and a fellowship in Pediatric Nephrology at Guy's Hospital, London, UK. She earned her Ph.D. in Molecular Genetics from Cambridge University (Christ's College) where she worked with Nobel Laureate Sydney Brenner on the synthetic mapping of human and puffer fish G proteins. Sarwal also holds a Diploma in Child Health from London, UK, and membership in the Royal College of Physicians, UK (MRCP). In 2009, she was formally elected as a Fellow of the Royal College of Physicians, UK in recognition of her outstanding contributions to the field of medicine.

Sarwal is a member of numerous national and international societies including the ASN, IPTA, AST, TTS, and IPNA. She has served as Associate Editor of American Journal of Transplantation and as a reviewer for Lancet, Nature Medicine, NEJM, Transplantation, Nature Genetics, PNAS, Kidney International and other prestigious peer-reviewed journals. Sarwal has also been the recipient of numerous awards and distinctions, including the Order of Excellence in Scientific Research (Cambridge, UK, 2002), the Dean's Teaching Award (2005), the Junior Faculty Award from the CCIS (2003-6), a Key Opinion Leader in Organ Transplantation by the Transplantation Society (2007-2009), an elected Senator at Large for the Stanford Faculty Senate (2005-10), the TTS-Roche Award for Outstanding Achievement Transplantation Science (Clinical; 2010), and the Cunio Richardson NKF Award for Scientific Excellence (2012).

Councillor
The Transplantation Society
2014
Cunio Richardson Award for Clinical and Research Excellence
The National Kidney Foundation
2012
TTS-Roche Award for Outstanding Achievement in Transplantation Science (Clinical)
The Transplantation Society
2010
KOL in Organ Transplantation
The Transplantation Society
2007 - 2010
Senator At Large, Stanford University Faculty Senate
Stanford University, USA
2005 - 2010
Deans Award for Resident Education
Stanford University, USA
2005
Faculty Development Award
CCIS, Stanford University, USA
2003 - 2006
Order of Excellence
Cambridge University, UK
2002
NKF Fellowship
National Kidney Foundation, UK
1993 - 1995
MRC Fellowship
Medical Research Council, UK
1991 - 1992

As principal Investigator on numerous multicenter clinical trials, both industry and institutional, Sarwal has developed extensive expertise in the design and execution of clinical studies. While at Stanford, Sarwal conducted the first successful U.S. steroid avoidance trial and the first dosing safety trial for Rituximab in pediatric renal transplantation.

In 2009, Sarwal founded, Organ-i, a Stanford University spin-out to develop and commercialize her pioneering work. Organ-i leveraged 15 years of research and over $20M in NIH grants. The company's goal is to improve the clinical management of transplant patients globally by commericializing non-invasive tests to monitor and predict organ health for transplant recipients.

Sarwal is credited with the introduction of (k-SORT), a Kidney Solid Organ Rejection Test, the company's lead product, as well as a pipeline of molecular assays focused on post-transplant rejection monitoring and allograft tolerance. In June 2014. Immucor, Inc., a global leader in transfusion and transplantation diagnostics, announced the acquisition of Organ-i and retained Sarwal as a scientific advisory role to advance the Organ-i pipeline.

Data provided by UCSF Profiles, powered by CTSI
ORCID iD: 0000-0003-3795-902X Additional info
  • Mapping Immune Responses to CMV in Renal Transplant Recipients
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    Aug 2017
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    Jul 2022
    Co-Principal Investigator
  • CD40 autoantibody and FSGS recurrence
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    Apr 2017
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    Mar 2022
    Principal Investigator
  • Filling a Void of Research (FAVOR) Training for Transplant Surgeons
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    Aug 2016
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    Jul 2021
    Co-Principal Investigator
  • Drug Repositioning in Diabetic Nephropathy
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    Sep 2016
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    Jul 2019
    Principal Investigator
  • Transplant injury biology and monitoring by urine proteomics
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    Jul 2009
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    Aug 2016
    Principal Investigator
  • Urinary Proteome Monitoring for Transplant Injury
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    Aug 2010
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    Jul 2015
    Principal Investigator
  • Gene and Cytokine Expression in Tolerance and GVHD
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    Sep 2009
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    Aug 2014
    Co-Principal Investigator
  • A Proteomics Research Resource for Integrative Biology
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    Sep 2003
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    Jun 2013
    Co-Investigator
  • General Clinical Research Center
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    Dec 1978
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    Nov 2011
    Co-Investigator
  • Novel Urinary Proteomic Biomarkers for Acute Renal Transplant Rejection
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    Jun 2009
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    May 2011
    Principal Investigator
  • Defining Biomarkers in Pediatric Renal Transplantation
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    Jun 2004
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    May 2009
    Principal Investigator
MOST RECENT PUBLICATIONS FROM A TOTAL OF 223
Data provided by UCSF Profiles, powered by CTSI
  1. Zarinsefat A, Hartoularos G, Yee CJ, Sarwal MM. Single-cell RNA sequencing of Tocilizumab-treated peripheral blood mononuclear cells as an in vitro model of inflammation. bioRxiv. 2020 Sep 11. View in PubMed
  2. Nolan N, Valdivieso K, Mani R, Yang JYC, Sarwal RD, Katzenbach P, Chalasani K, Hongo D, Lugtu G, Mark C, Chen E, Nijor R, Savoca D, Wexler DS, Whitson T, Huang SJ, Lu LH, Zawada RJX, Hytopoulos E, Sarwal MM. Clinical and Analytical Validation of a Novel Urine-Based Test for the Detection of Allograft Rejection in Renal Transplant Patients. J Clin Med. 2020 Jul 22; 9(8). View in PubMed
  3. Sigdel TK, Schroeder AW, Yang JYC, Sarwal RD, Liberto JM, Sarwal MM. Targeted Urine Metabolomics for Monitoring Renal Allograft Injury and Immunosuppression in Pediatric Patients. J Clin Med. 2020 Jul 22; 9(8). View in PubMed
  4. Mannon RB, Armstrong B, Stock PG, Mehta AK, Farris AB, Watson N, Morrison Y, Sarwal M, Sigdel T, Bridges N, Robien M, Newell KA, Larsen CP. Avoidance of CNI and steroids using belatacept-Results of the Clinical Trials in Organ Transplantation 16 trial. Am J Transplant. 2020 Jun 18. View in PubMed
  5. Yang JYC, Sarwal RD, Sigdel TK, Damm I, Rosenbaum B, Liberto JM, Chan-On C, Arreola-Guerra JM, Alberu J, Vincenti F, Sarwal MM. A urine score for noninvasive accurate diagnosis and prediction of kidney transplant rejection. Sci Transl Med. 2020 Mar 18; 12(535). View in PubMed
  6. View All Publications

 

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