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Sarwal Lab »  Lab Members »  Principal Investigators »  Minnie M. Sarwal M.D., Ph.D.
Minnie M. Sarwal M.D., Ph.D., FRCP, DCH

Minnie M. Sarwal M.D., Ph.D., FRCP, DCH

Professor of Surgery, Medicine, Pediatrics
Professor (Adj), Stanford University, UC Berkeley
Director, Precision Transplant Medicine, UCSF
Co-Director, T32 Training Grant, Transplant Surgery, UCSF

Contact Information

Box 0780
513 Parnassus Ave, Med Sci Room S1268
San Francisco, CA 94143
minnie.sarwal@ucsf.edu
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La Martiniere, Calcutta, India, English Language and Literature, I.S.C.,1981

Calcutta Medical College, Calcutta, India, M.D.,1985

Diploma in Child Health (D.C.H.), London, UK, with distinction 1989

Cambridge University, U.K, Ph.D.,1995

  • Residency (Medicine and Surgery), Calcutta Medical College, India, 06/1986-06/1987
  • Senior House Officer (Pediatrics and Surgery), Calcutta Medical College, India. Advisors: Sir Keith Peters, Sir Cyril Chantler and Sydney Brenner, 06/1987-02/1988
  • Senior House Officer, General Pediatrics & Neonates, Good Hope Hospital, Sutton Coldfield, Birmingham, UK, 02/-07/1989
  • Senior House Officer, General Pediatrics & Neonates, Grantham and Kesteven Hospital, Granthan (GKGH), UK, 03/1988-02/1989
  • Senior House Officer, Neonatology, Leicester Royal Infirmary (LRI), Leicester, UK, 08/-11/1989
  • Senior House Officer, General Pediatrics & Neonates, Leicester General Hosp. (LGH), Leicester, UK, 12/89- 03/90
  • Registrar, Pediatric Cardiology and Cardiothoracic Surgical Unit, Groby Road Hospital, (GRH), Leicester, UK, 04/90-07/90
  • Senior House Officer, Pediatric Nephrology Unit, Guy's Hospital, London, UK, 08/90-10/90
  • Lecturer/Registrar, Pediatric Unit, Guy's Hospital, London, UK, 10/90-09/91
  • Lecturer/Senior Registrar,  Pediatric Nephrology, Dept. of Pediatrics, Guy's Hospital, London, U.K., 10/92-07/95
  • Fellowship in Nephrology, Department of Pediatrics, Addenbrooke's Hospital, Cambridge, 10/91-09/92
  • Ph.D., Molecular Genetics Unit, Christs College, Cambridge University, 10/92-12/95 
  • Acute Kidney Failure
  • Chronic Kidney Disease
  • Cystinosis
  • End-Stage Renal Disease
  • Kidney Transplant Clinical Trials
  • Methylmalonic acidemia
  • Oxalosis
  • Pediatric Bone and Mineral Disorders
  • Pediatric Kidney Transplantation
  • Pediatric Transplant Nephrology
  • Transplant Immunology
  • Genomics
  • Antibiomics
  • GVHD
  • Hepatitis B, C and HIV
  • Metabolomics
  • Organ diseases
  • Proteomics
  • Transplant immunobiology of rejection and tolerance
  • Hindi, Punjab

Minnie M. Sarwal M.D., Ph.D., FRCP, DCH is professor of Surgery, director of the Sarwal Lab, and Precision Transplant Medicine at UCSF. Sarwal is a nationally and internationally recognized leader in the fields of renal and transplant medicine, genomics, proteomics and immunology. She as a deep passion for improving the health of organ transplant recipients by discovering new treatments and investigative approaches for improving outcomes. Prior to joining UCSF, Sarwal was Professor of Surgery, Pediatrics and Immunology at Stanford University, Medical Director of the Pediatric Kidney Transplant Program at Lucille Packard Children's Hospital and Director of the Sarwal Lab.

Sarwal received her M.D. from Calcutta Medical College in India, completed her residency in the UK, and a fellowship in Pediatric Nephrology at Guy's Hospital, London, UK. She earned her Ph.D. in Molecular Genetics from Cambridge University (Christ's College) where she worked with Nobel Laureate Sydney Brenner on the synthetic mapping of human and puffer fish G proteins. Sarwal also holds a Diploma in Child Health from London, UK, and membership in the Royal College of Physicians, UK (MRCP). In 2009, she was formally elected as a Fellow of the Royal College of Physicians, UK in recognition of her outstanding contributions to the field of medicine.

Sarwal is a member of numerous national and international societies including the ASN, IPTA, AST, TTS, and IPNA. She has served as Associate Editor of American Journal of Transplantation and as a reviewer for Lancet, Nature Medicine, NEJM, Transplantation, Nature Genetics, PNAS, Kidney International and other prestigious peer-reviewed journals. Sarwal has also been the recipient of numerous awards and distinctions, including the Order of Excellence in Scientific Research (Cambridge, UK, 2002), the Dean's Teaching Award (2005), the Junior Faculty Award from the CCIS (2003-6), a Key Opinion Leader in Organ Transplantation by the Transplantation Society (2007-2009), an elected Senator at Large for the Stanford Faculty Senate (2005-10), the TTS-Roche Award for Outstanding Achievement Transplantation Science (Clinical; 2010), and the Cunio Richardson NKF Award for Scientific Excellence (2012).

  Award  
  Confired By    
  Date    
  • Councillor
  • The Transplantation Society
  • 2014
  • Cunio Richardson Award for Clinical and Research Excellence
  • The National Kidney Foundation
  • 2012
  • TTS-Roche Award for Outstanding Achievement in Transplantation Science (Clinical)
  • The Transplantation Society
  • 2010
  • KOL in Organ Transplantation
  • The Transplantation Society
  • 2007 - 2010
  • Senator At Large, Stanford University Faculty Senate
  • Stanford University, USA
  • 2005 - 2010
  • Deans Award for Resident Education
  • Stanford University, USA
  • 2005
  • Faculty Development Award
  • CCIS, Stanford University, USA
  • 2003 - 2006
  • Order of Excellence
  • Cambridge University, UK
  • 2002
  • NKF Fellowship
  • National Kidney Foundation, UK
  • 1993 - 1995
  • MRC Fellowship
  • Medical Research Council, UK
  • 1991 - 1992
  • As principal Investigator on numerous multicenter clinical trials, both industry and institutional, Sarwal has developed extensive expertise in the design and execution of clinical studies. While at Stanford, Sarwal conducted the first successful U.S. steroid avoidance trial and the first dosing safety trial for Rituximab in pediatric renal transplantation.

    In 2009, Sarwal founded, Organ-i, a Stanford University spin-out to develop and commercialize her pioneering work. Organ-i leveraged 15 years of research and over $20M in NIH grants. The company's goal is to improve the clinical management of transplant patients globally by commericializing non-invasive tests to monitor and predict organ health for transplant recipients.

    Sarwal is credited with the introduction of (k-SORT), a Kidney Solid Organ Rejection Test, the company's lead product, as well as a pipeline of molecular assays focused on post-transplant rejection monitoring and allograft tolerance. In June 2014. Immucor, Inc., a global leader in transfusion and transplantation diagnostics, announced the acquisition of Organ-i and retained Sarwal as a scientific advisory role to advance the Organ-i pipeline.

    Data provided by UCSF Profiles, powered by CTSI
    ORCID iD: 0000-0003-3795-902X Additional info
    • Mapping Immune Responses to CMV in Renal Transplant Recipients
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      Aug 2017
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      Jul 2022
      Co-Principal Investigator
    • CD40 autoantibody and FSGS recurrence
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      Apr 2017
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      Mar 2022
      Principal Investigator
    • Filling a Void of Research (FAVOR) Training for Transplant Surgeons
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      Aug 2016
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      Jul 2021
      Co-Principal Investigator
    • Drug Repositioning in Diabetic Nephropathy
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      Sep 2016
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      Jul 2019
      Principal Investigator
    • Transplant injury biology and monitoring by urine proteomics
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      Jul 2009
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      Aug 2016
      Principal Investigator
    • Urinary Proteome Monitoring for Transplant Injury
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      Aug 2010
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      Jul 2015
      Principal Investigator
    • Gene and Cytokine Expression in Tolerance and GVHD
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      Sep 2009
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      Aug 2014
      Co-Principal Investigator
    • A Proteomics Research Resource for Integrative Biology
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      Sep 2003
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      Jun 2013
      Co-Investigator
    • General Clinical Research Center
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      Dec 1978
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      Nov 2011
      Co-Investigator
    • Novel Urinary Proteomic Biomarkers for Acute Renal Transplant Rejection
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      Jun 2009
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      May 2011
      Principal Investigator
    • Defining Biomarkers in Pediatric Renal Transplantation
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      Jun 2004
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      May 2009
      Principal Investigator
    MOST RECENT PUBLICATIONS FROM A TOTAL OF 227
    Data provided by UCSF Profiles, powered by CTSI
    1. El-Achkar TM, Eadon MT, Menon R, Lake BB, Sigdel TK, Alexandrov T, Parikh S, Zhang G, Dobib D, Dunn KW, Otto EA, Anderton CR, Carson JM, Luo J, Park C, Hamidi H, Zhou J, Hoover P, Schroeder A, Joanes M, Azeloglu EU, Sealfon R, Winfree S, Steck B, He Y, D'Agati VD, Iyengar R, Troyanskaya OG, Barisoni L, Gaut J, Zhang K, Laszik Z, Rovin B, Dagher PC, Sharma K, Sarwal M, Hodgin JB, Alpers CE, Kretzer M, Jain S, The Kidney Precision Medicine Project F. A Multimodal and Integrated Approach to Interrogate Human Kidney Biopsies with Rigor and Reproducibility: Guidelines from the Kidney Precision Medicine Project. Physiol Genomics. 2020 Nov 16. View in PubMed
    2. Meier RPH, Noguchi H, Kelly YM, Sarwal M, Conti G, Ward C, Halleluyan R, Tavakol M, Stock PG, Freise CE. Impact of Sarcopenia on Simultaneous Pancreas and Kidney Transplantation Outcomes: A Retrospective Observational Cohort Study. Transplant Direct. 2020 Oct; 6(10):e610. View in PubMed
    3. Sigdel TK, Piehowski PD, Roy S, Liberto J, Hansen JR, Swensen AC, Zhao R, Zhu Y, Rashmi P, Schroeder A, Damm I, Sur S, Luo J, Yang Y, Qian WJ, Sarwal MM. Near-Single-Cell Proteomics Profiling of the Proximal Tubular and Glomerulus of the Normal Human Kidney. Front Med (Lausanne). 2020; 7:499. View in PubMed
    4. Zarinsefat A, Hartoularos G, Yee CJ, Sarwal MM. Single-cell RNA sequencing of Tocilizumab-treated peripheral blood mononuclear cells as an in vitro model of inflammation. bioRxiv. 2020 Sep 11. View in PubMed
    5. Pineda S, Sur S, Sigdel T, Nguyen M, Crespo E, Torija A, Meneghini M, Gomà M, Sirota M, Bestard O, Sarwal MM. Peripheral Blood RNA Sequencing Unravels a Differential Signature of Coding and Noncoding Genes by Types of Kidney Allograft Rejection. Kidney Int Rep. 2020 Oct; 5(10):1706-1721. View in PubMed
    6. View All Publications

     

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