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Sarwal Lab »  Lab Members »  Principal Investigators »  Tara Sigdel, Ph.D.
Tara Sigdel, Ph.D.

Tara Sigdel, Ph.D.

Associate Professor of Surgery
Division of Transplant Surgery

Contact Information

513 Parnassus Ave, Med Sci
San Francisco CA 94143
tara.sigdel@ucsf.edu
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B.Sc. (Biology and Chemistry) Tribhuvan University, Kathmandu, Nepal

M.Sc. (Chemistry) Tribhuvan University, Kathmandu, Nepal, Advisor: Prof. Vishwanath Pd. Agrawal, PhD

Ph.D. (Biochemistry), Miami University, Oxford, OH, Advisor: Prof. Michael Crowder, PhD

  • N/A
  • Postdoctoral Training, Dept of Pediatrics-nephrology, Stanford University, Stanford, CA
  • Advisor: Prof. Minnie Sarwal MD. PhD.
  • Bioinformatics
  • Biomarker DIscovery
  • High Throughput Data
  • Immunology
  • Kidney Transplantation
  • Liver Cancer
  • Organ Transplantation
  • Proteomics

Tara Sigdel, Ph.D. obtained his Ph.D. in biochemistry from Miami University (OH) followed by postdoctoral training in biomarker discovery, immunology, and organ transplantation at Stanford University under Professor Minnie Sarwal. Dr Sigdel joined the UCSF Department of Surgery in 2014 where he uses proteomics, immune response profiling, and gene expression analysis to discover sensitive and effective biomarkers that help in developing clinical tools for early diagnosis and improved patient monitoring. In collaboration with researchers at UCSF and other institutes, Dr. Sigdel is actively involved in identification of non-invasive biomarkers genes, peptides, proteins, and antibodies that monitor disease status after organ transplantation.

  Award  
  Confired By    
  Date    
  • Pediatric Research Fund – CHRP Award
  • Stanford University, Stanford, CA
  • 2009 - 2010
  • Pediatric Research Fund – CHRP Award
  • Stanford University, Stanford, CA
  • 2008 - 2009
  • Deans Postdoctoral Fellowship
  • Stanford University, Stanford, CA
  • 2007 - 2008
  • Doctoral-Undergraduate Opportunities in Scholarship (DUOS) award for two consecutive years (2003 and
  • Miami University, Oxford, OH
  • 2003 - 2005
  • William Hale Charch Graduate Fellowship
  • Miami University, Oxford, OH
  • 2002 - 2003
  • Dr. Sigdel's research is driven by two major factors. First, there is an unprecedented pressure to deliver new and improved diagnostic and treatment options to patients. Second, due to improved understanding of biological intricacies with ever improving molecular assays have placed us in a much better position to look for disease specific biomarkers that once validated can be used in the clinics in order to provide timely and accurate assessment of health status of patients.

    MOST RECENT PUBLICATIONS FROM A TOTAL OF 89
    Data provided by UCSF Profiles, powered by CTSI
    1. Swensen AC, He J, Fang AC, Ye Y, Nicora CD, Shi T, Liu AY, Sigdel TK, Sarwal MM, Qian WJ. A Comprehensive Urine Proteome Database Generated From Patients With Various Renal Conditions and Prostate Cancer. Front Med (Lausanne). 2021; 8:548212. View in PubMed
    2. Zarinsefat A, Guerra JMA, Sigdel T, Damm I, Sarwal R, Chan-On C, Szabo G, Aguilar-Frasco JL, Ixtlapale-Carmona X, Salinas-Ramos C, Ramirez-Martinez L, Ramirez C, Vilatoba M, Morales Buenrostro LE, Alberu JM, Sarwal MM. Use of the Tissue Common Rejection Module Score in Kidney Transplant as an Objective Measure of Allograft Inflammation. Front Immunol. 2020; 11:614343. View in PubMed
    3. Sigdel TK, Piehowski PD, Roy S, Liberto J, Hansen JR, Swensen AC, Zhao R, Zhu Y, Rashmi P, Schroeder A, Damm I, Sur S, Luo J, Yang Y, Qian WJ, Sarwal MM. Corrigendum: Near-Single-Cell Proteomics Profiling of the Proximal Tubular and Glomerulus of the Normal Human Kidney. Front Med (Lausanne). 2020; 7:625788. View in PubMed
    4. El-Achkar TM, Eadon MT, Menon R, Lake BB, Sigdel TK, Alexandrov T, Parikh S, Zhang G, Dobi D, Dunn KW, Otto EA, Anderton CR, Carson JM, Luo J, Park C, Hamidi H, Zhou J, Hoover P, Schroeder A, Joanes M, Azeloglu EU, Sealfon R, Winfree S, Steck B, He Y, D'Agati V, Iyengar R, Troyanskaya OG, Barisoni L, Gaut J, Zhang K, Laszik Z, Rovin BH, Dagher PC, Sharma K, Sarwal MM, Hodgin JB, Alpers CE, Kretzler M, Jain S. A multimodal and integrated approach to interrogate human kidney biopsies with rigor and reproducibility: guidelines from the Kidney Precision Medicine Project. Physiol Genomics. 2021 01 01; 53(1):1-11. View in PubMed
    5. Sigdel TK, Salomonis N, Nicora CD, Ryu S, He J, Dinh V, Orton DJ, Moore RJ, Hsieh SC, Dai H, Thien-Vu M, Xiao W, Smith RD, Qian WJ, Camp DG, Sarwal MM. The Identification of Novel Potential Injury Mechanisms and Candidate Biomarkers in Renal Allograft Rejection by Quantitative Proteomics. Mol Cell Proteomics. 2014 Feb; 13(2):621-631. View in PubMed
    6. View All Publications

     

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