University of California San Francisco

Grants & Funding

1R01AI180118-01A1

NIH Natl Inst Allergy & Infectious Diseases.(NIH-NIAID)

06/28/202406/30/2029

Principal Investigator

Computational Drug Repositioning for Antibody Mediated Renal Allograft Rejection

Major Goals:
1. To develop and apply a drug repurposing pipeline to ABMR expression profiles to query publicly available drug-gene expression databases, to identify single and combination drug repurposing candidates for ABMR. 
2. To determine the mechanism of action of promising drugs or drug combinations in human tissue, ex vivo, in immune cells and ABMR patient-derived endothelial cellsand to validate their effect on preventing and/or treating ABMR by their study in vivo, in a pre-clinical, validated, animal model of ABMR. 

1T32AI125222 - 01 

NIAID-T32 Training Grant

08/01/2016 - 07/31/2026

PI/CO-Director

Filling a Void of Research Training for Transplant Surgeons (FAVOR)

Major Goals: Training grant for transplant surgeons

HRCI-HRB-2024-013 

Health Research Charities Ireland and Cystinosis Ireland

2/1/2025 - 01/31/2027

Principal Investigator

Evaluate the protective effect of Astaxanthin for the treatment for nephropathic cystinosis in a cystinotic rat model 

IM103-339

Bristol-Myers Squibb Company

05/27/2014 - 06/30/2027

Principal Investigator

BEST Sub Study - Minimally invasive diagnosis of acute rejection and new onset of diabetes mellitus after transplantation (NODAT) in kidney transplantation (BMS IM103-339)

Major Goals: To identify molecular markers for detecting early markers of NODAT after kidney transplantation.